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Fuji's Astaxanthin Study References
Cardiovascular - Fuji
Hussein, G. et al., 2005a, Antihypertensive and Neuroprotective Effects of Astaxanthin in Experimental Animals. Biol. Pharm. Bull. 2005; 28(1): 47-52.
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Hussein G., et al., 2005b. Antihypertensive potential and mechanism of action of astaxanthin II. Vascular reactivity and hemorheology in spontaneously hypertensive rats. Biol. Pharm. Bull. 28(6):967-971.
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Hussein G., et al., 2006a, Antihypertensive potential and mechanism of action of astaxanthin: III. Antioxidant and histopathological effects in spontaneously hypertensive rats. Biol. Pharm. Bull. 29(4):684-688.
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Hussein G., et al., 2006b, Astaxanthin, a carotenoid with potential in human health and nutrition. J.Nat.Prod.69(3):443-449
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Li W., et al., Alpha-tocopherol and astaxanthin decrease macrophage infiltration, apoptosis and vulnerability in atheroma of hyperlipidaemic rabbits. Journal of Molecular and Cellular Cardiology 2004; 37: 969-978.
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Miyawaki, H. et al. Effects of Astaxanthin on Human Blood Rheology. Journal of Clinical Therapeutics and Medicines 2005; 21 (4):421-429.
Nagaki, Y. et al. The Effect of Astaxanthin on Retinal Capillary Blood Flow in Normal Volunteers. Journal of Clinical Therapeutics and Medicines 2005; 21 (5): 537-542.
Diabetic Nephropathy - Fuji
Naito, Y. et al., Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice. BioFactors 2004; 20:49-59.
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Uchiyama K., et al., Astaxanthin protects cells against glucose toxicity in diabetic db/db mice. Redox Report 2002; 7(5):290-292.
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Muscle endurance - Fuji
Aoi et al. Astaxanthin Limits exercise-induced skeletal and cardiac muscle damage in mice. Antioxidants & Redox Signal 2003; 5(1): 139-144.
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Ikeuchi, M. et al., Effects of astaxanthin supplementation on exercise-included fatigue in mice. Biol. Pharm. Bull. 2006 Oct; 29(10): 2106-10.
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Sawaki et al. Sports performance benefits from taking natural astaxanthin characterized by visual acuity and muscle fatigue improvements in humans. Journal of Clinical Therapeutics & Medicines 2002; 18 (9): 1085-1100.
Eye Fatigue - Fuji
Iwasaki & Tawara., Effects of astaxanthin on eyestrain induced by accommodative dysfunction. Journal of Eye (Atarashii Ganka) 2006
Nagaki et al. Effects of Astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. Journal of Traditional Medicines 2002; 19(5):170-173.
Nagaki et al. The effect of astaxanthin on retinal capillary blood flow in normal volunteers. Journal of Clinical Therapeutics and Medicines 2005; 21(5):537-542.
Nagaki et al. The supplementation effect of astaxanthin on accommodation and asthenopia. 2006; Journal of Clinical Therapeutics and Medicines 22(1):41-54.
Nakamura et al. Changes in visual function following peroral astaxanthin. Japan Journal of Clinical Opthalmology 2004; 58(6):1051-1054.
Nitta et al. Effect of astaxanthin on accommodation and asthenopia - Efficacy – identification study in healthy volunteers. Journal of Clinical Therapeutics and Medicines 2005; 21(6):637-650.
Sawaki et al. Sports performance benefits from taking natural astaxanthin characterized by visual acuity and muscle fatigue improvements in humans. Journal of Clinical Therapeutics & Medicines 2002; 18(9):1085-1100.
Shiratori et al. Effect of astaxanthin on accommodation and asthenopia – Dose finding study in healthy volunteers. Journal of Clinical Therapeutics and Medicines 2005; 21(5):543-556.
Takahashi, Kajita Effects of Astaxanthin on accommodative recovery. Journal of Clinical Therapeutics and Medicines 2005; 21(4):431-436.
Gastric - Fuji
Bennedsen et al. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunology Letters 2000; 70(3):185-189.
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Wang et al. Astaxanthin rich algal meal and vitamin C inhibit H.pyori infection in BABLB/cA mice. Antimicrobial Agents and Chemotherapy 2000; 44(9):2452- 2457.
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Skin - Fuji
Seki et al., 2001. Effects of astaxanthin fromf Haematococcus pluvialis on human skin. Fragrance Journal 12:98-103
Yamashita, E. Cosmetic benefit of dietary supplements including astaxanthin and tocotrienol on human skin. 2002, FOOD Style 21, 6:(6) 112-117.
Yamashita, E. Effect of a Dietary Supplement Containing Astaxanthin on Skin Condition. Carotenoid Science 2006. Vol. 10: 91-95.
Lipid Metabolism (BMI) - Fuji
Aoi et al. Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification. Biochemical & Biophysical Research Communications 36:892-897.
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Anti-Inflammation - Fuji
Bennedsen et al. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunology Letters 1999; 70(3):185-189.
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Wang et al. Astaxanthin rich algal meal and vitamin C inhibit H.pyori infection in BABLB/cA mice. Antimicrobial Agents and Chemotherapy 2000; 44(9):2452- 2457.
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Antioxidant - Fuji
Nishida et al. Quenching Activities of Common Hydrophilic and Lipophilic Antioxidants against Singlet Oxygen Using Chemiluminescence Detection System. Carotenoid Science. 2007; Vol. 11: 16-20.
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